Subvolts take Pause life's clock: explore cryopreservation's potential for medicine and longevity. Jan 29, 2026 - Business
- Learn how engineering principles are applied to solve complex biological problems, potentially creating new markets in medicine and longevity.
- Everyday users
- Understand the future of medicine, including how organ transplantation and aging might be addressed with advanced preservation technologies.
This interview features a startup CEO discussing a potentially transformative medical technology with significant implications for longevity and healthcare.
Why Cryopreservation is No Longer Science Fiction with Until Co-founder and CEO Laura Deming
Audio streams from Conviction. Your place is remembered on this device.
From Subvolts
Summary and analysis by Subvolts editorial, AI-assisted.
Sarah Guo and Elad Gil discuss reversible cryopreservation with Laura Deming, CEO of Until. Deming explains her work on pausing biological time, starting with organs, to address aging and improve organ transplantation. The conversation covers scientific challenges, engineering approaches to biology, and scaling the technology for potential medical hibernation.
Imagine being able to freeze a body part, like an organ, to keep it fresh until it's needed for a transplant. This episode talks about new ways to do that, not just for organs but maybe for whole bodies, to give people more time when facing serious illness.
This episode explores the cutting edge of cryopreservation, a field with profound implications for medicine and longevity. Listeners will learn about the scientific hurdles and engineering solutions involved in pausing biological time. It is for anyone interested in radical life extension and the future of healthcare. While not directly about current AI models, the engineering approach to biological problems mirrors how AI is applied to complex scientific challenges, showing a similar drive to solve previously intractable issues.
- HostSarah Guo
- HostElad Gil
- GuestLaura DemingCEO and co-founder, Until
- Episode Title: Why Cryopreservation is No Longer Science Fiction with Until Co-founder and CEO Laura Deming
- Show: No Priors
- Length: 31 minutes
- Guest Organization: Until
- Guest Role: CEO and co-founder
What if we could pause biological time to wait for a cure for a disease? Thanks to innovations and research in reversible cryopreservation, this possibility is no longer just science fiction. Sarah Guo sits down with Laura Deming, CEO and co-founder of biotech startup Until, to dive deep into the growing field of reversible cryopreservation. Laura talks about how her time as a Thiel Fellow as well as her founding of the Longevity Fund fueled her obsession with solving the “social blindspot” of aging. Laura details how her new startup, Until, seeks to build tools that allow for “pressing pause” on biological time, starting with human organs with the hopes of scaling up to full body medical hibernation. Together, they also discuss why ice is the enemy of tissue, using engineering tools to help solve biological problems, and how this technology may revolutionize organ transplantation by removing time as a variable.
Sign up for new podcasts every week. Email feedback to show@no-priors.com
Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @LauraDeming | @untillabs
Chapters:
00:00 – Cold Open
01:08 – Laura Deming Introduction
01:53 – Why Laura Focused on Cryo Preservation and Longevity
06:20 – Bringing on Co-Founder Hunter Davis
07:55 – Until’s Goal
10:10 – Other Use Cases for Cryo Technology
12:22 – Scientific Challenges in Cryo Tech
15:36 – Using Engineering Principles to Solve Biological Problems
20:18 – Scaling Up Cryo Preservation
21:48 – Leading and Recruiting at Until
25:02 – Why Hasn’t Cryo Tech Been Worked On More?
27:14 – Making Time Not a Variable in Organ Transplants
29:06 – Changing How the Molecular World is Depicted
30:47 – Conclusion
- Cryopreservation
- Laura Deming
- Freezing biological material to preserve it.
- Reversible cryopreservation
- Laura Deming
- Freezing biological material in a way that it can be safely thawed and still function.
39 min1 h 1136 minQuestions people ask
- What is Until's goal with cryopreservation?
- Until aims to build tools that allow for pausing biological time, starting with human organs and hoping to scale up to full body medical hibernation.
- How might cryopreservation revolutionize organ transplantation?
- It could revolutionize organ transplantation by removing time as a variable, ensuring organs remain viable for longer periods.
Page generated Oct 19, 2026. Summaries are Subvolts' own; the audio, artwork and notes belong to Conviction.