24 minHow AI Is Rewriting the Rules of Cybersecurity | Truffle Security & Socket
WithDylan Ayrey, Feross Aboukhadijeh
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AI + a16z
Andreessen Horowitz partners and guests on AI infrastructure, models and products.
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1 h47 minAll 47 episodes
How AI Is Rewriting the Rules of Cybersecurity | Truffle Security & Socket
AI is actively hacking, forcing a cybersecurity evolution.
Hostsa16zGuestsDylan Ayrey (co-founder and CEO, Truffle Security), Feross Aboukhadijeh (founder and CEO, Socket)
Inside vLLM: The Engine Powering Open-Source AI
Open-source inference engines like vLLM are becoming essential AI infrastructure, empowering developers.
Hostsa16zGuestsSimon Mo (co-founder and CEO, Inferact)
Building Self-Accelerating AI with Mirendil
AI that improves itself could unlock scientific breakthroughs faster than humans alone.
Hostsa16zGuestsBehnam Neyshabur (cofounder, Mirendil), Harsh Mehta (cofounder, Mirendil)
Ideogram’s Open-Weights Image Model and the Future of AI Design
Ideogram's CEO discusses open-weight image models and the future of AI design control.
Hostsa16zGuestsMohammad Norouzi (founder and CEO, Ideogram)
Building Search for AI Agents with Exa CEO Will Bryk
Search is evolving beyond humans to power AI agents, a foundational layer for the agent economy.
Hostsa16zGuestsWill Bryk (cofounder and CEO, Exa)
AI Agents and the Fight for Customer Data
AI agents need solid data foundations, not just access, for enterprise success.
Hostsa16zGuestsGeorge Fraser (cofounder and CEO, Fivetran)
Ben Horowitz on AI Infrastructure, Economics and The New Laws of Software
AI is rewriting software rules, and crypto infrastructure is key.
Hostsa16zGuestsBen Horowitz (cofounder and general partner, a16z)
AI Infrastructure, Distribution, and the Next Wave of Software
AI infrastructure and distribution are now key advantages for building the next wave of software.
Hostsa16zGuestsJennifer Li (General Partner, a16z)
From Vector Databases to Knowledge Engines: The Next Layer of AI
AI agents need knowledge engines, not just databases, for efficient machine-to-machine interaction.
Hostsa16zGuestsAsh Ashutosh (CEO, Pinecone)
Why We Need Continual Learning
AI needs to learn from experience, moving beyond static systems to adapt over time.
Hostsa16zGuestsMalika Aubakirova (partner on the AI infrastructure team, a16z)
The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie
Agents will transform enterprise software, making data access and systems of record agent-first.
Hostsa16zGuestsAaron Levie (CEO, Box)
Rethinking Git for the Age of Coding Agents with GitHub Cofounder Scott Chacon
Modernizing Git for AI agents means rethinking developer tools for the next generation of coding.
Hostsa16zGuestsScott Chacon (CEO, GitButler)
How AI Is Reshaping IT Services from the Inside
AI is modernizing the massive IT services market, blending human expertise with automation.
Hostsa16zGuestsPeter Doyle (CEO, Treeline)
Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding
Stripe CEO Patrick Collison shares lessons on enduring tech choices and AI's real-world economic impact.
Hostsa16zGuestsPatrick Collison (CEO, Stripe)
OpenClaw: Why the Internet Isn't Built for AI Agents
AI agents need a new internet; current sites resist integration, creating a developer bottleneck.
Hostsa16zGuestsYoko Li, Guido Appenzeller, Joel de la Garza
What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado
Understand LLM limits and the real path to AGI beyond pattern matching.
Hostsa16zGuestsVishal Misra
Replit's CEO on Vibe Coding, Wealth Building, and What Most People Get Wrong About AI
AI empowers creation, making software accessible to more people.
Hostsa16zGuestsAmjad Masad (CEO, Replit)
Jack Altman & Martin Casado on the Future of VC
VCs are evolving. Learn how media and talent battles define AI infrastructure investment.
Hostsa16zGuestsJack Altman, Martin Casado (General Partner, a16z)
AI’s Capital Flywheel: Models, Money, and the Future of Power
AI funding dynamics are unprecedented, with model developers outraising their entire ecosystems.
Hostsa16zGuestsMartin Casado (a16z), Sarah Wang (a16z)
Durable Execution and the Infrastructure Powering AI Agents
AI agents need robust infrastructure to run reliably; this episode explains how.
Hostsa16zGuestsSamar Abbas (CEO, Temporal)
Evals, Feedback Loops, and the Engineering That Makes AI Work
Understand AI engineering's real impact and future challenges.
Hostsa16zGuestsAnkur Goyal (founder and CEO, Braintrust)
Sam Altman on Sora, Energy, and Building an AI Empire
OpenAI's CEO details Sora, strategy, and the future of AI development.
Hostsa16zGuestsSam Altman (OpenAI)
Why This Isn't the Dot-Com Bubble | Martin Casado on WSJ's BOLD NAMES
AI spending is not a dot-com bubble due to stronger fundamentals, says a16z partner Martin Casado.
Hostsa16zGuestsMartin Casado (General Partner, a16z)
Martin Casado on the Demand Forces Behind AI
AI's growth faces regulatory hurdles, not just technical ones, reshaping enterprise software.
Hostsa16zGuestsMartin Casado (General Partner, a16z)
How Mintlify Is Rebuilding Documentation for Coding Agents
See how AI agents are making documentation essential infrastructure for software development.
Hostsa16zGuestsHan Wang (Cofounder, Mintlify), Hahnbee Lee (Cofounder, Mintlify)
Inferact: Building the Infrastructure That Runs Modern AI
Inferact's founders explain how to run AI models faster and cheaper with open-source infrastructure.
Hostsa16zGuestsMatt Bornstein (Inferact), Simon Mo (Inferact), Woosuk Kwon (Inferact)
How Should AI Be Regulated? Use vs. Development
Regulate AI by focusing on misuse, not development, applying existing laws and targeting specific risks.
Hostsa16zGuestsMartin Casado (General Partner, a16z)
Michael Truell: How Cursor Builds at the Speed of AI
Cursor's CEO shares how they built the fastest growing developer tool by focusing on power users.
Hostsa16zGuestsMichael Truell (CEO, Cursor)
Dylan Patel on the AI Chip Race - NVIDIA, Intel & the US Government
Nvidia's Intel investment reshapes the AI chip race, impacting global competition and tech policy.
Hostsa16zGuestsDylan Patel (chief analyst, SemiAnalysis), Sarah Wang (general partner, a16z), Guido Appenzeller (partner, a16z)
Feed Drop from The Generalist: Why a16z's Martin Casado believes the AI boom still has years to run
AI's boom has years to run, with coding markets poised for massive growth.
Hostsa16zGuestsMartin Casado (General Partner, a16z)
Fei-Fei Li: World Models and the Multiverse
AI needs to understand space, not just words, for its next big leap.
Hostsa16zGuestsFei-Fei Li (cofounder and CEO, World Labs)
Building the “See Something, Say Something” AI for Every Camera
AI makes security cameras smart, detecting and stopping threats before they happen.
Hostsa16zGuestsShikhar Shrestha (CEO and cofounder, Ambient)
The AI That Found A Bug In The World’s Most Audited Code
AI now finds security bugs in heavily audited code, potentially easing cybersecurity's talent shortage.
Hostsa16zGuestsMatt Knight (Leader of Aardvark, OpenAI)
The Death of Data Gatekeeping: AI Makes Everyone An Analyst | Hex Cofounder
AI is making everyone a data analyst by replacing dashboards with conversational tools.
Hostsa16zGuestsBarry McCardel (CEO, Hex)
Why Social Engineering Now Works on Machines
AI models are vulnerable to social engineering; learn how to find and fix these flaws.
Hostsa16zGuestsIan Webster (founder, PromptFoo)
“Anyone Can Code Now” - Netlify CEO Talks AI Agents
AI agents are turning everyday users into coders, expanding the developer market exponentially.
Hostsa16zGuestsMatt Biilmann (CEO, Netlify)
From Code Search to AI Agents: Inside Sourcegraph's Transformation with CTO Beyang Liu
Chinese AI models dominate open-source coding, a shift driven by US policy fears.
Hostsa16zGuestsBeyang Liu (CTO, Sourcegraph)
Ryo Lu (Cursor): AI Turns Designers to Developers
AI tools like Cursor let designers code at the speed of thought, changing software creation.
Hostsa16zGuestsRyo Lu (Head of Design, Cursor)
How Foundation Models Evolved: A PhD Journey Through AI's Breakthrough Era
Make AI programmable: learn about DSPy, a new way to control LLMs beyond simple prompts.
Hostsa16zGuestsOmar Khattab (Stanford PhD, Stanford)
TruffleHog Creator: You Can’t Have AI Agents Without Secrets
Secure AI agents need strong secret protection; learn why leaks are worsening.
Hostsa16zGuestsDylan Ayrey (cofounder and CEO, Truffle Security)
Tigris Data CEO on Building Your Own Datacenters
Understand private data center challenges and cloud's future from a storage expert.
Hostsa16zGuestsOvais Tariq (Cofounder and CEO, Tigris Data)
Pylon: Reimagining B2B Customer Support
Pylon's founders share their strategy for disrupting B2B customer support with AI.
Hostsa16zGuestsMarty Kausas (cofounder, Pylon), Advith Chelikani (cofounder, Pylon), Robert Eng (cofounder, Pylon)
Keycard: 2026 is the Year of Agents
AI agents will dominate enterprise in 2026, demanding new management tools.
Hostsa16zGuestsIan Livingstone (Cofounder and CEO, Keycard)
The Trillion Dollar AI Software Development Stack
AI agents are reshaping software development, creating new tools and economic models for engineers.
Hostsa16zGuestsYoko Li (Infra Partner, a16z), Guido Appenzeller (Infra Partner, a16z)
Material Security CEO: How To Find Your Ideal Customer
Find your ideal customer before you build. Learn to read market signals.
Hostsa16zGuestsAbhishek Agrawal (Cofounder and CEO, Material Security)
When Deepfakes Steal $30M: The New Edge of Cybercrime
AI fuels cybercrime; this episode shows how AI fights back with smarter defenses.
Hostsa16zGuestsKevin Tian (cofounder & CEO, Doppel Security)
How AI Will Change Photography Forever
AI is redefining photography, moving beyond filters to personalized memory capture and AI-driven image creation.
Hostsa16zGuestsRen Ng (scientist, Lytro), Cecilia Zhang (cofounder, Phota Labs), Zhihao “Zach” Xia (cofounder, Phota Labs)
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