41 minWhat racing reveals about working with AI - Episode 22
WithJoyce Ruffell, Chase Holden
The OpenAI Podcast
OpenAI's own people on what they are building and why, straight from the lab.
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Best episodes
41 min44 minWhy Tejal Patwardhan stopped underestimating the models - Episode 21
WithTejal Patwardhan
41 minHow a reasoning model cracked an 80-year-old math problem - Episode 20
WithAlexander Wei, Hongxun Wu, Lijie Chen
29 minInside image generation’s Renaissance moment - Episode 19
WithAdele Li, Kenji Hata
38 minWhy AI needs a new kind of supercomputer network - Episode 18
WithMark Handley, Greg Steinbrecher
43 minWhat happens now that AI is good at math? - Episode 17
WithSébastien Bubeck, Ernest Ryu
Latest
44 minBuilding AI for Life Sciences - Episode 16
WithJoy Jiao, Yunyun Wang
37 minInside the Model Spec - Episode 15
WithJason Wolfe
31 minBuilding AI for better healthcare - Episode 14
WithNate Gross, Karan Singhal
26 minThe Thinking Behind Ads in ChatGPT - Episode 13
WithAsad Awan
50 minState of the AI Industry - Episode 12
WithSarah Friar, Vinod Khosla
29 minShaping Model Behavior in GPT-5.1 - Episode 11
WithChristina Kim, Laurentia Romaniuk
All 23 episodes
What racing reveals about working with AI - Episode 22
AI helps racing teams win by analyzing data and giving smaller teams a competitive edge.
HostsAndrew MayneGuestsJoyce Ruffell (OpenAI researcher, OpenAI), Chase Holden (RaceTek Systems co-founder, RaceTek Systems)
Why Tejal Patwardhan stopped underestimating the models - Episode 21
AI evaluation is getting harder. Listen to how OpenAI tests its frontier models.
HostsAndrew MayneGuestsTejal Patwardhan (leads OpenAI’s frontier evals team, OpenAI)
How a reasoning model cracked an 80-year-old math problem - Episode 20
AI helped solve an 80-year-old math problem, showing AI's power in scientific discovery.
HostsAndrew MayneGuestsAlexander Wei (reasoning researcher, OpenAI), Hongxun Wu (reasoning researcher, OpenAI), Lijie Chen (reasoning researcher, OpenAI)
Inside image generation’s Renaissance moment - Episode 19
See how AI image generation is evolving from DALL-E to creative assistants.
HostsAndrew MayneGuestsAdele Li (Product lead, OpenAI), Kenji Hata (Researcher, OpenAI)
Why AI needs a new kind of supercomputer network - Episode 18
OpenAI details a new network protocol to keep massive AI training runs stable and efficient.
HostsAndrew MayneGuestsMark Handley (OpenAI), Greg Steinbrecher (OpenAI)
What happens now that AI is good at math? - Episode 17
AI now solves complex math problems, accelerating research and hinting at future discovery.
HostsAndrew MayneGuestsSébastien Bubeck (OpenAI), Ernest Ryu (OpenAI)
Building AI for Life Sciences - Episode 16
OpenAI's leaders discuss AI's role in accelerating life sciences research and drug discovery.
HostsAndrew MayneGuestsJoy Jiao (Research lead, OpenAI), Yunyun Wang (Product lead, OpenAI)
Inside the Model Spec - Episode 15
OpenAI details its public Model Spec for guiding AI behavior and adapting to new capabilities.
HostsAndrew MayneGuestsJason Wolfe (researcher, OpenAI)
Building AI for better healthcare - Episode 14
OpenAI leaders detail how AI can solve healthcare's biggest problems, from patient care to system efficiency.
HostsAndrew MayneGuestsNate Gross (Head of Health, OpenAI), Karan Singhal (Health AI Research Lead, OpenAI)
The Thinking Behind Ads in ChatGPT - Episode 13
OpenAI details its plan to integrate ads into ChatGPT while protecting user privacy.
HostsAndrew MayneGuestsAsad Awan (ad leads, OpenAI)
State of the AI Industry - Episode 12
AI leaders discuss scaling compute, expanding benefits, and future applications in health and robotics.
HostsAndrew MayneGuestsSarah Friar (CFO, OpenAI), Vinod Khosla (Founder, Khosla Ventures)
Shaping Model Behavior in GPT-5.1 - Episode 11
OpenAI tunes GPT-5.1 for personality, balancing intelligence with emotional response.
HostsAndrew MayneGuestsChristina Kim (Researcher, OpenAI), Laurentia Romaniuk (Product Manager, OpenAI)
How AI Is Accelerating Scientific Discovery Today and What's Ahead - Episode 10
OpenAI researchers detail how GPT-5 is speeding up science and what's next.
HostsAndrew Mayne
ChatGPT Atlas and the next era of web browsing - Episode 9
OpenAI's browser vision: AI makes the web interactive and agents handle tasks.
HostsAndrew MayneGuestsBen Goodger (OpenAI), Darin Fisher (OpenAI)
OpenAI x Broadcom and the future of compute - Episode 8
OpenAI partners with Broadcom to build custom AI chips, accelerating the path to AGI.
HostsAndrew MayneGuestsHock Tan (Broadcom), Charlie Kawwas (Broadcom)
Live from DevDay - Episode 7
See how AI startups are building practical tools for coding, healthcare, and education.
HostsAndrew MayneGuestsCaleb Hicks (SchoolAI), Dani Grant (Jam.dev), Zach Lipton (Abridge), Lee Robinson (Cursor)
The future of coding with AI - Episode 6
AI is becoming a true coding partner, capable of complex tasks and collaborative development.
HostsAndrew MayneGuestsGreg Brockman (co-founder, OpenAI), Thibault Sottiaux (Codex engineering lead, OpenAI)
Defining AGI and the road ahead - Episode 5
OpenAI researchers detail the path to AGI and automating scientific discovery.
HostsAndrew MayneGuestsJakub Pachocki (Chief Scientist, OpenAI), Szymon Sidor (Researcher, OpenAI)
How AI is transforming education - Episode 4
Learn how AI tutors build confidence and redefine learning with OpenAI's Head of Education.
HostsAndrew MayneGuestsYabsera (college student), Alaap (college student)
Jobs, growth, and the AI economy - Episode 3
AI's economic impact is here: learn how it affects jobs, business, and education.
HostsAndrew MayneGuestsBrad Lightcap (COO, OpenAI), Ronnie Chatterji (Chief Economist, OpenAI)
Inside ChatGPT, AI assistants, and building at OpenAI - Episode 2
OpenAI leaders reveal ChatGPT's surprising journey and future AI assistant plans.
HostsAndrew MayneGuestsNick Turley (Head of ChatGPT, OpenAI), Mark Chen (Chief Research Officer, OpenAI)
Sam Altman on AGI, GPT-5, and what’s next - Episode 1
OpenAI's CEO shares insights on GPT-5, AGI, and future AI hardware.
HostsAndrew MayneGuestsSam Altman (OpenAI)
The OpenAI Podcast Is Coming
OpenAI launches its own podcast to share insights directly with the AI community.
HostsAndrew Mayne
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