1 h 08David Silver and Lasse Espeholt of Ineffable Intelligence: A Superlearner for the Age of Experience
WithDavid Silver, Lasse Espeholt
PodcastBoard #20
Training Data
Sequoia partners talk with the founders building the next generation of AI companies.
Follow Training Data
Best episodes
1 h 081 h 041 h 0552 minMaking Cities Awesome: Peregrine’s Nick Noone & Ben Rudolph
WithNick Noone, Ben Rudolph
55 minParallel’s Parag Agrawal: Building a New Web for AI Agents
WithParag Agrawal
54 minRich Sutton and Khurram Javed: Why AI Models Stop Learning, and How to Start It Again
WithRich Sutton, Khurram Javed
Latest
47 minChai Discovery's Bitter Lesson: Drug Design Is Another Scaling Problem
WithJosh Meier, Matt McPartlon
49 minBuilding the Automated AGI Lab: Core Automation's Jerry Tworek and Rohan Anil
WithJerry Tworek, Rohan Anil
52 min49 minAnthropic's Katelyn Lesse & Angela Jiang: Building an Ecosystem, not a Walled Garden
WithKatelyn Lesse, Angela Jiang
55 minInside Zipline's Autonomous System: 140M Miles, Zero Incidents
WithKeller Rinaudo Cliffton, Eric Watson
1 h 10All 47 episodes
David Silver and Lasse Espeholt of Ineffable Intelligence: A Superlearner for the Age of Experience
AI that learns everything from scratch, not from human data, could be the path to superintelligence.
HostsSequoia CapitalGuestsDavid Silver (Co-founder, Ineffable Intelligence), Lasse Espeholt (Co-founder, Ineffable Intelligence)
Google's AI Infrastructure Chief, Amin Vahdat, on the Physics & Economics of Frontier AI
Google's AI infrastructure chief explains why "goodput" matters more than FLOPS for frontier AI.
HostsSequoia CapitalGuestsAmin Vahdat (Chief Technologist for AI Infrastructure, Google)
Box's Aaron Levie: On Reinventing Yourself in the AI Age and Enterprise Diffusion
Box CEO explains building AI applications that beat raw models for enterprise workflows.
HostsSequoia CapitalGuestsAaron Levie (CEO, Box)
Making Cities Awesome: Peregrine’s Nick Noone & Ben Rudolph
Peregrine uses AI to connect existing city data for public safety, prioritizing privacy and sovereignty.
HostsSequoia CapitalGuestsNick Noone (Co-founder, Peregrine), Ben Rudolph (Co-founder, Peregrine)
Parallel’s Parag Agrawal: Building a New Web for AI Agents
AI agents need a new web infrastructure; Parallel is building it and rethinking online economics.
HostsSequoia CapitalGuestsParag Agrawal (founder and CEO, Parallel Web Systems)
Rich Sutton and Khurram Javed: Why AI Models Stop Learning, and How to Start It Again
AI needs to learn continuously, not from frozen data, to reach its full potential.
HostsSequoia CapitalGuestsRich Sutton (Oak Lab), Khurram Javed (Oak Lab)
Chai Discovery's Bitter Lesson: Drug Design Is Another Scaling Problem
AI scaling transforms drug design from a needle-in-a-haystack search to an engineering problem.
HostsSequoia CapitalGuestsJosh Meier (co-founder, Chai Discovery), Matt McPartlon (co-founder, Chai Discovery)
Building the Automated AGI Lab: Core Automation's Jerry Tworek and Rohan Anil
AI's next leap requires new architectures beyond transformers for continual learning, not just more scale.
HostsSequoia CapitalGuestsJerry Tworek (led reasoning, OpenAI), Rohan Anil (co-led Gemini pre-training, Google)
Factory's Matan Grinberg: The Coming ‘Dark Factory’ Where Software Builds Itself
Autonomous coding agents are coming, and a flexible approach beats tightly coupled AI.
HostsSequoia CapitalGuestsMatan Grinberg (CEO, Factory)
Anthropic's Katelyn Lesse & Angela Jiang: Building an Ecosystem, not a Walled Garden
Anthropic builds an open AI ecosystem by sharing standards, not by owning the whole stack.
HostsSequoia CapitalGuestsKatelyn Lesse (Anthropic), Angela Jiang (Anthropic)
Inside Zipline's Autonomous System: 140M Miles, Zero Incidents
Zipline's 140M mile, zero-incident drone system shows autonomous delivery's real-world enterprise potential.
HostsSequoia CapitalGuestsKeller Rinaudo Cliffton (Co-founder, Zipline), Eric Watson (Lead, Systems Engineering and Safety, Zipline)
Why Hardware-Software Co-Design Is AI's Real 100x: Dylan Patel of SemiAnalysis
Software and hardware co-design, not just faster chips, unlocks AI's 100x potential.
HostsSequoia CapitalGuestsDylan Patel (founder, SemiAnalysis)
Memory and Continual Learning: Engram's Dan Biderman and Jessy Lin
Build AI that learns like an employee, not just a bigger chatbot.
HostsSequoia CapitalGuestsDan Biderman (co-founder, Engram), Jessy Lin (co-founder, Engram)
Simulating Humans at Scale: Simile's Joon Sung Park
Simulating human society requires a new AI approach beyond raw intelligence, says Simile's founder.
HostsSequoia CapitalGuestsJoon Sung Park (founder and CEO, Simile)
Google DeepMind's Logan Kilpatrick: Why the Model Eats the Harness
Google's Logan Kilpatrick sees AI models absorbing agent tools, shifting focus to vertical intelligence.
HostsSequoia CapitalGuestsLogan Kilpatrick (leads Google AI Studio and the Gemini API, Google)
LIVE: Jensen Huang on Building the Dynamo of the Intelligence Age
NVIDIA's CEO explains AI factories as the new dynamos powering intelligence's next global shift.
HostsSequoia CapitalGuestsJensen Huang (founder and CEO, NVIDIA)
Knowing What Your Customers Want, All the Time: Listen Labs' Alfred Wahlforss
AI interviews reveal customer truths humans miss, driving product strategy.
HostsSequoia CapitalGuestsAlfred Wahlforss (co-founder and CEO, Listen Labs)
How Cursor Trained Composer on Fireworks: Distributed Infrastructure for High-Performance RL
Specialized AI models can outperform larger ones by focusing training on specific tasks.
HostsSequoia CapitalGuestsFederico Cassano (Cursor), Dmytro Dzhulgakov (Fireworks)
Rebuilding IT From the Ground Up for the AI Age: Serval's Jake Stauch
Build AI-powered enterprise tools with a dual-agent system and focus on hiring.
HostsSequoia CapitalGuestsJake Stauch (founder and CEO, Serval)
Suno's Mikey Shulman: Everyone Can Make Music Now
Suno's AI makes music creation the entertainment, like gaming.
HostsSequoia CapitalGuestsMikey Shulman (Founder and CEO, Suno)
ElevenLabs' Mati Staniszewski: How Voice Becomes the Interface for Everything
Voice AI is the next computing interface; ElevenLabs shows how to build a business around it.
HostsSequoia CapitalGuestsMati Staniszewski (co-founder and CEO, ElevenLabs)
Anthropic's Boris Cherny: Coding's Printing Press Moment
AI is solving coding, making it as easy as using a printing press.
HostsSequoia CapitalGuestsBoris Cherny (creator of Claude Code, Anthropic)
Waymo's Dmitri Dolgov: 20 Million Rides and the Road to Full Autonomy
Waymo's journey shows AI's slow but steady progress toward real-world safety and scale.
HostsSequoia CapitalGuestsDmitri Dolgov (co-CEO, Waymo)
OpenAI's Greg Brockman: Why Human Attention Is the New Bottleneck
OpenAI sees human attention as the next bottleneck as AI capabilities rapidly advance.
HostsSequoia CapitalGuestsGreg Brockman (co-founder and president, OpenAI)
Demis Hassabis on Building DeepMind, AlphaFold, and the Final Stretch to AGI
AGI by 2030? DeepMind's Hassabis shares his bold predictions and the future of AI.
HostsSequoia CapitalGuestsDemis Hassabis (co-founder and CEO, Google DeepMind)
Andrej Karpathy: From Vibe Coding to Agentic Engineering
Karpathy explains agentic engineering and how to direct LLMs like summoned ghosts.
HostsSequoia CapitalGuestsAndrej Karpathy (Founder, Eureka Labs)
From SEO to Agent-Led Growth: Profound’s James Cadwallader
AI agents are rewriting marketing; focus on original insights, not just SEO.
HostsSequoia CapitalGuestsJames Cadwallader (co-founder and CEO, Profound)
How Autonomous Labs Will Transform Scientific Research: Ginkgo Bioworks’ Jason Kelly
AI automates lab work, slashing scientific discovery costs and accelerating breakthroughs.
HostsSequoia CapitalGuestsJason Kelly (Founder, Ginkgo Bioworks)
Greetings, Earthlings: Philip Johnston of Starcloud on Data Centers in Space
Space will become the primary location for AI compute infrastructure due to lower costs.
HostsSequoia CapitalGuestsPhilip Johnston (founder and CEO, Starcloud)
Physics Gets a Vote: Nominal Cofounders on Hardware Development in an AI World
Hardware needs software-like development for AI's physical future.
HostsSequoia CapitalGuestsCameron McCord (Cofounder, Nominal), Jason Hoch (Cofounder, Nominal), Bryce Strauss (Cofounder, Nominal)
Building the GitHub for RL Environments: Prime Intellect's Will Brown & Johannes Hagemann
Build custom AI by turning company knowledge into training data.
HostsSequoia CapitalGuestsWill Brown (Prime Intellect), Johannes Hagemann (Prime Intellect)
What’s the Future of Vertical SaaS in an AGI World? Jamie Cuffe, CEO of Pace
AI agents are tackling insurance BPO, promising big cost savings and building trust in regulated sectors.
HostsSequoia CapitalGuestsJamie Cuffe (CEO, Pace)
Making the Case for the Terminal as AI's Workbench: Warp’s Zach Lloyd
AI agents are making the terminal the new developer workbench, potentially solving coding soon.
HostsSequoia CapitalGuestsZach Lloyd (founder, Warp)
Context Engineering Our Way to Long-Horizon Agents: LangChain’s Harrison Chase
Agent development prioritizes context engineering over just better models for long-term autonomy.
HostsSequoia CapitalGuestsHarrison Chase (cofounder, LangChain)
How Ricursive Intelligence’s Founders are Using AI to Shape The Future of Chip Design
AI is now designing the chips that power AI, making hardware development faster and more accessible.
HostsSequoia CapitalGuestsAnna Goldie (Founder, Ricursive Intelligence), Azalia Mirhoseini (Founder, Ricursive Intelligence)
Training General Robots for Any Task: Physical Intelligence’s Karol Hausman and Tobi Springenberg
Robots can learn general skills, not just specific tasks, using foundation models.
HostsSequoia CapitalGuestsKarol Hausman (Physical Intelligence), Tobi Springenberg (Physical Intelligence)
Why the Next AI Revolution Will Happen Off-Screen: Samsara CEO Sanjit Biswas
Physical AI is transforming industries by optimizing operations and coaching workers, moving beyond screen-based applications.
HostsSequoia CapitalGuestsSanjit Biswas (CEO, Samsara)
The Rise of Generative Media: fal's Bet on Video, Infrastructure, and Speed
fal builds the infrastructure for generative video, enabling faster model deployment than training labs.
HostsSequoia CapitalGuestsGorkem Yurtseven (founder, fal), Burkay Gur (founder, fal), Batuhan Taskaya (Head of Engineering, fal)
Why IDEs Won't Die in the Age of AI Coding: Zed Founder Nathan Sobo
IDEs remain vital for AI coding, offering a human-readable layer for persistent code conversations.
HostsSequoia CapitalGuestsNathan Sobo (Founder, Zed)
How End-to-End Learning Created Autonomous Driving 2.0: Wayve CEO Alex Kendall
Wayve's AI approach to autonomous driving adapts to new cities and vehicles faster than traditional methods.
HostsSequoia CapitalGuestsAlex Kendall (CEO, Wayve)
How Google’s Nano Banana Achieved Breakthrough Character Consistency
Learn how Google's Nano Banana achieved character consistency and what it means for visual AI.
HostsSequoia CapitalGuestsNicole Brichtova (product lead, Google), Hansa Srinivasan (engineering lead, Google)
OpenAI Sora 2 Team: How Generative Video Will Unlock Creativity and World Models
OpenAI's Sora 2 team reveals how AI video generation advances physics understanding and sparks new creative economies.
HostsSequoia CapitalGuestsBill Peebles (OpenAI), Thomas Dimson (OpenAI), Rohan Sahai (OpenAI)
Nvidia CTO Michael Kagan: Scaling Beyond Moore's Law to Million-GPU Clusters
Nvidia's CTO explains the complex hardware needed to build massive AI systems.
HostsSequoia CapitalGuestsMichael Kagan (CTO, Nvidia)
Securing the AI Frontier: Irregular Co-founder Dan Lahav
AI's autonomous agents demand new security thinking, moving beyond traditional defenses.
HostsSequoia CapitalGuestsDan Lahav (co-founder, Irregular)
Why AI Will Transform Customer Experience: Cresta CEO Ping Wu and Sequoia’s Doug Leone
AI augments human agents for better customer service, not just full automation.
HostsSequoia CapitalGuestsPing Wu (CEO, Cresta)
Block CTO Dhanji Prasanna: Building the AI-First Enterprise with Goose, their Open Source Agent
Block's CTO shares how AI agents boost enterprise productivity and why small AI swarms will win.
HostsSequoia CapitalGuestsDhanji Prasanna (CTO, Block)
Why Businesses Are Rejecting the AI They’ve Asked For: Agency CEO Elias Torres
Businesses want AI but fear its flaws; this episode explores overcoming that gap.
HostsSequoia CapitalGuestsElias Torres (Agency CEO, Agency)
Page generated Oct 19, 2026. Feed checked every six hours.